| Effect of snail mucus on wound healing and inflammation |
| Paper ID : 1109-ISCHU |
| Authors |
|
Sheriene Essam Ali * Helwan university faculty of science |
| Abstract |
| Wound healing is a physiological process that involves numerous synchronized phases, including inflammation, proliferation, and remodeling. Helix aspersa (Muller 1774) mucus has been recognized for years to have biological activities that can be used to treat skin diseases. The aim of the work was to examine snail secretion filtrate (SSF) as a wound healing agent. A full-thickness excisional wound model was employed in mice, and the SSF was topically put on the wounds. Inflammatory cytokines were measured in wounded and treated tissues using the ELISA technique. The mice were treated topically with SSF for 14 days following the injury. Macroscopic findings demonstrate that SSF greatly improved wound speed and the percentage of wound area closure. The scratch wound assay proved the speed of healing in comparison with control. SSF could also modulate the inflammatory markers in wounded tissue (IL1, IL10, and TNF). Finally, our findings suggest that SSF can improve the speed and efficiency of wound healing and, in addition, positively regulate numerous components of the wound healing process, such as the proliferative and remodeling stages. |
| Keywords |
| helix aspersa , wound healing , snail secretion filtrate |
| Status: Abstract Accepted (Poster Presentation) |